vhl ligand 2 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7752	(S,R,S)-AHPC-Me	VHL ligand 2,E3 ligase Ligand 1A	Ligand for E3 Ligase
	(S,R,S)-AHPC-Me (E3 ligase Ligand 1A) (VHL ligand 2) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein[1]. (S,R,S)-AHPC-Me can be used to synthesize ARV-771. ARV-771 is a...		Ligand for E3 Ligase
T13671	(S,R,S)-AHPC-Me hydrochloride	VHL ligand 2 hydrochloride,E3 ligase Ligand 1	Others , Ligand for E3 Ligase
	(S,R,S)-AHPC-Me hydrochloride (VHL ligand 2 hydrochloride) is a chemical compound utilized in the synthesis of ARV-771, an exceptionally potent BET protein degrader. This compound selectively degrades BET protein in cell...		Others , Ligand for E3 Ligase
T17924	(S,R,S)-AHPC-PEG2-NH2 hydrochloride	VH032-PEG2-NH2 hydrochloride,VHL Ligand-Linker Conjugates 3 hydrochloride,E3 ligase Ligand-Linker Conjugates 6	Others , E3 Ligase Ligand-Linker Conjugate
	(S,R,S)-AHPC-PEG2-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 6) is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG2-NH2 hydrochloride incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit...		Others , E3 Ligase Ligand-Linker Conjugate
T17925	(S,R,S)-AHPC-PEG2-NH2	VH032-PEG2-NH2,VHL Ligand-Linker Conjugates 3,E3 ligase Ligand-Linker Conjugates 6 Free Base	Others , E3 Ligase Ligand-Linker Conjugate
	(S,R,S)-AHPC-PEG2-NH2 (VHL Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG2-NH2 incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis ...		Others , E3 Ligase Ligand-Linker Conjugate
T13671L	(S,R,S)-AHPC-Me dihydrochloride	VHL ligand 2 dihydrochloride,E3 ligase Ligand 1 dihydrochloride,(S,R,S)-AHPC-Me dihydrochloride (1948273-02-6 free base)	Others
	(S,R,S)-AHPC-Me dihydrochloride, also known as VHL ligand 2 dihydrochloride, is a chemical compound utilized in the synthesis of ARV-771. ARV-771, a BET PROTAC degrader relying on von Hippel-Landau (VHL) E3 ligase, demon...		Others
T17912	(S,R,S)-AHPC-(C3-PEG)2-C6-Cl	VHL Ligand-Linker Conjugates 11,E3 ligase Ligand-Linker Conjugates 11	Others
	(S,R,S)-AHPC-(C3- PEG) 2- C6- Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-(C3- PEG) 2- C6- Cl is capable of inducing the degradation of GFP-Ha...		Others
T17905	(S,R,S)-AHPC-PEG1-OTs	VH032-PEG1-OTs,VHL Ligand-Linker Conjugates 2,E3 ligase Ligand-Linker Conjugates 51	Others
	(S,R,S)-AHPC-PEG1-OTs is a chemically synthesized conjugate, functioning as an ligase ligand-linker for E3 ligase. It incorporates the VHL ligand derived from (S,R,S)-AHPC and a 1-unit PEG linker. This synthesized compou...		Others
T17913	(S,R,S)-AHPC-PEG2-N3	VHL Ligand-Linker Conjugates 6,VH032-PEG2-N3,E3 ligase Ligand-Linker Conjugates 13	Others , Ligand for E3 Ligase
	(S,R,S)-AHPC-PEG2-N3 (VHL Ligand-Linker Conjugates 6) is a synthesized E3 ligase ligand-linker conjugate containing a (S,R,S)-AHPC based VHL ligand and 2 unit PEG linker.		Others , Ligand for E3 Ligase
T17910	(S,R,S)-AHPC-PEG2-C4-Cl	E3 ligase Ligand-Linker Conjugates 10,VHL Ligand-Linker Conjugates 7,VH032-PEG2-C4-Cl	Others
	(S,R,S)-AHPC-PEG2-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-PEG2-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-bas...		Others
T18675	(S,R,S)-AHPC-PEG2-NH2 dihydrochloride	VH032 amide-PEG2-amine,VH032-PEG2-NH2 dihydrochloride,VH032-linker 12	Others , Ligand for E3 Ligase
	(S,R,S)-AHPC-PEG2-NH2 dihydrochloride (VH032-linker 12) is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker[1].		Others , Ligand for E3 Ligase
T40217	PD0325901-O-C2-dioxolane	PD0325901-O-C2-dioxolane
	PD0325901-O-C2-dioxolane is a chemical compound primarily composed of the MEK inhibitor PD0325901. It can be utilized, in conjunction with either a VHL or CRBN E3 ligase ligand, for the synthesis of MEK1/2 degrader.
T18668	(S,R,S)-AHPC-Me-C10-Br		Others
	(S,R,S)-AHPC-Me-C10-Br is a chemically synthesized conjugate that functions as a ligand-linker for E3 ligases. This compound incorporates a VHL E3 ligase linker and MS432, derived from the MEK1/2 inhibitor PD0325901[1].		Others
T17996	VH032-PEG5-C6-Cl	HaloPROTAC 2	Others
	VH032-PEG5-C6-Cl (HaloPROTAC 2) is a small molecule HaloPROTAC that incorporates the VH032 based VHL ligand and 5-unit PEG linker. VH032-PEG5-C6-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based ass...		Others
T73945	MAK683-CH2CH2COOH hydrochloride
	MAK683-CH2CH2COOH, targeting embryonic ectoderm development protein (EED), alongside a VHL ligand for E3 ubiquitin ligase, contributes to the formulation of PROTAC EED degrader-1 and PROTAC EED degrader-2 [1].
T36270	(S,R,S)-AHPC-phenol-alkylC6-amine dihydrochloride	VH 032 phenol-alkylC6-amine
	Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand. Part of a range of funct...
T13765	MAK683-CH2CH2COOH		Others
	MAK683-CH2CH2COOH binds to EED (embryonic ectoderm development protein). MAK683-CH2CH2COOH and a VHL ligand for the E3 ubiquitin ligase have been used to design EED-Targeted PROTAC which are EED degrader-1 and PROTAC EED...		Others
T36267	VH 032 amide-PEG4-amine	VH 032 amide-PEG4-amine
	Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of function...
T18055	K-Ras ligand-Linker Conjugate 2		Others
	K-Ras ligand-Linker Conjugate 2 is a chemical compound that includes a ligand for K-Ras and a PROTAC linker. This compound is capable of recruiting E3 ligases like VHL, CRBN, MDM2, and IAP. It is utilized in the synthesi...		Others